Download e-book for kindle: ABC Proteins: From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher

By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins

ISBN-10: 0123525519

ISBN-13: 9780123525512

ABC Proteins is an in-depth, updated research of all that's identified in regards to the topic thus far. It discusses and compares evolution, biology and mechanism of motion of all recognized ABC proteins, together with the 1st structural experiences in addition to scientific implications. it will likely be valuable to someone attempting to remain abreast of the most recent findings. This publication is certain to turn into a vintage and should usually be up-to-date. Key gains* Phylogeny and Evoloution of ABC Transporters* basic features of the Mechanism of motion of ABC Transporters* Prokaryote ABC Transporters* Non-Mammalian Transporters* Multidrug Transporters* ABC Transporters, Physiological Roles and Human ailment* complete colour all through

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Additional resources for ABC Proteins: From Bacteria to Man

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Bacteriol. 173, 372–381. L. H. (1998) Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 396, 703–707. , Dassa, E. and Schneider, E. (2000) ATP modulates subunit–subunit interactions in an ATPbinding cassette transporter (MalFGK2) determined by site-directed chemical crosslinking. J. Biol. Chem. 275, 15526–15534. , Ito, K. and Kashiwagi, K. (2001) Polyamine uptake systems in Escherichia coli. Res. Microbiol. 152, 271–278. , Matsuzawa, Y. and Kurachi, Y. 2) a smooth muscle type ATP-sensitive Kϩ channel.

2001). A typical system consists of one gene encoding the ABC and one gene encoding the IM. 8C. In addition to these proteins, capsular polysaccharide exporter systems require two ‘accessory’ proteins to perform their function: a periplasmic (E. coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and H. , 1997). The proteins that are common to the CLS family (IM and ABC) segregate within two distinct clusters corresponding to capsular polysaccharide exporters and lipopolysaccharide exporters, respectively.

173, 372–381. L. H. (1998) Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 396, 703–707. , Dassa, E. and Schneider, E. (2000) ATP modulates subunit–subunit interactions in an ATPbinding cassette transporter (MalFGK2) determined by site-directed chemical crosslinking. J. Biol. Chem. 275, 15526–15534. , Ito, K. and Kashiwagi, K. (2001) Polyamine uptake systems in Escherichia coli. Res. Microbiol. 152, 271–278. , Matsuzawa, Y. and Kurachi, Y. 2) a smooth muscle type ATP-sensitive Kϩ channel.

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ABC Proteins: From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins


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