Read e-book online Alkaloids : biosynthesis, biological roles and health PDF

By Eduardo Sobarzo-sanchez

ISBN-10: 1634820754

ISBN-13: 9781634820752

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LeBoeuf, L. Gay, T. Yagi, and B. Felding-Habermann, Mitochondrial complex I activity and NAD +/NADH balance regulate breast cancer progression. J. Clin. , 123 (2013) 1068-81. [32] F. Weinberg, R. Hamanaka, W. Wheaton, S. Weinberg, J. Joseph, M. Lopez, B. Kalyanaraman, G. Mutlu, G. Budinger, and N. Chandel, Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proc. Natl. Acad. Sci. U S A, 107 (2010) 8788-93. [33] S. J. Ralph, S. RodrĂ­guez-EnrĂ­quez, J. Neuzil, E.

Evidente, and L. Pottier, Lycorine and its derivatives for anticancer drug design. Mini Rev. Med. , 10 (2010) 41-50. [139] J. McNulty, J. Nair, J. Bastida, S. Pandey, and C. Griffin, Structure-activity studies on the lycorine pharmacophore: A potent inducer of apoptosis in human leukemia cells. Phytochemistry, 70 (2009) 913-9. [140] X. S. Liu, J. Jiang, X. Y. Jiao, Y. E. Wu, J. H. Lin, and Y. M. Cai, Lycorine induces apoptosis and down-regulation of Mcl-1 in human leukemia cells. , 274 (2009) 16-24.

In addition, alkaloids are known as highly scavengers of reactive oxygen and nitrogen species (such as hydroxyl radical and peroxynitrite ) and from this way, possess a wide range of health -promoting effects. Boldine is one of the most important antioxidant alkaloids, widely distributed in the Chilean medicinal plant, commonly known as boldo. There are several scientific studies about the in vitro antioxidant effects of boldine as well as in vivo protective role of this alkaloid against oxidative stress.

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Alkaloids : biosynthesis, biological roles and health benefits by Eduardo Sobarzo-sanchez


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